Photodynamic Therapy with Verteporfin for Anterior Segment Neovascularization in Neovascualr Galucoma.

Song, Yoo Mi; Kim, Joon Hyun

Case Report

Journal of the Korean Ophthalmological Society 2005;46(9):1592-1596.
Published online September 30, 2005.

Photodynamic Therapy with Verteporfin for Anterior Segment Neovascularization in Neovascualr Galucoma.

Yoo Mi Song, Joon Hyun Kim

Department of Ophthalmology, Hanyang University College of Medicine, Seoul, Korea. joshua115@hanyang.ac.kr

신생혈관녹내장에서 광역학치료를 이용한 치험 1예

송유미,김준현

Department of Ophthalmology, Hanyang University College of Medicine, Seoul, Korea

Correspondence: Yoo-Mi Song, M.D.

Abstract

PURPOSE
To evaluate photodynamic therapy (PDT) with verteporfin for iris and angle neovascularization in eyes with neovascular glaucoma. METHODS: We treat a patient who had neovascular glaucoma with iris and angle neovacularization and showed reduction of intraocular pressure (IOP) and the obliteration of neovascularization after PDT. PDT was performed following the treatment parameters used in age-related macular degeneration. The laser was directed at the anterior chamber angle and iris surface using a Goldmann three-mirror contact lens. Follow-up examination was performed 1, 2, 3, 5, 7, and 8 weeks after PDT, and included visual acuity, IOP, and iris fluorescein angiography (7 weeks after PDT). RESULTS: Two months after PDT, we observed a reduction of IOP and the improvement of iris fluorescein leakage. IOP diminished considerably after 1 week, and showed subsequent tendency toward stabilization without additional antiglaucoma medicine. CONCLUSIONS: Photodynamic therapy can be used safely and effectively in the early phase of neovascular glaucoma to achieve the obliteration of iris and angle neovascularization and induce IOP reduction.

Key Words: Neovascular glaucoma;Photodynamic therapy;Verteporfin