Photodynamic Therapy for Choroidal Neovascularization in Angioid Streaks.

Jung, Ja Young; Cho, Sung Won; Lee, Jae Heung

doi:2007.48.11.1593

J Korean Ophthalmol Soc > Volume 48(11); 2007 > Article

Case Report

Journal of the Korean Ophthalmological Society 2007;48(11):1593-1598.
DOI: https://doi.org/10.3341/jkos.2007.48.11.1593 Published online November 30, 2007.

Photodynamic Therapy for Choroidal Neovascularization in Angioid Streaks.

Ja Young Jung, Sung Won Cho, Jae Heung Lee

Myung-Gok Eye Research Institute, Department of Ophthalmology, Konyang University, Kim's Eye Hospital, Seoul, Korea. eyecure@hotmail.com

혈관줄무늬망막병증에서 발생한 맥락막신생혈관의 광역학치료 6예

정자영,조성원,이재흥

Myung-Gok Eye Research Institute Department of Ophthalmology, Konyang University, Kim’s Eye Hospital, Seoul, Korea

Correspondence: Sung Won Cho, M.D., Ph.D.

Abstract

PURPOSE
To evaluate the efficacy of photodynamic therapy (PDT) with verteporfin in the management of choroidal neovascularization (CNV) associated with angioid streaks. CASE SUMMARY: Six eyes of four patients with CNV due to angioid streaks were treated with photodynamic therapy with verteporfin. Visual acuity testing, ophthalmologic examinations, photographs, and fluorescein angiograms were used to evaluate the results of PDT. Two of six eyes had subfoveal lesions, while four eyes had juxtafoveal lesions on initial examination. Conversion from a CNV to a fibrous scar lesion following PDT was observed in four eyes. Enlargement of the CNV was documented in two eyes at the final follow-up. Of a total of 6 eyes, the final best-corrected visual acuity decreased in 4 eyes and stabilized in 2 eyes. CONCLUSIONS: Photodynamic therapy can achieve short-term cessation or decrease of fluorescein leakage from chroidal neovascularization associated with angioid streaks. However, it does not alter the course of this disease, and multiple sessions are needed. Visual prognosis is poor.

Key Words: Angioid streaks;Photodynamic therapy