Journal of the Korean Ophthalmological Society 2006;47(3):423-430.
Published online March 31, 2006.
The Clinical Analysis and Treatment Results of Coats' Disease in Children.
Eui Seok Han, Ho Kyung Choung, Jang Won Heo, Seong Joon Kim, Young Suk Yu
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. ysyu@snu.ac.kr
2Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea.
3Seoul Municipal Boramae Hospital, Seoul, Korea.
코우츠병의 임상분석 및 치료결과
한의석1,2,정호경3,허장원3,김성준1,2,유영석1,2
Department of Ophthalmology, Seoul National University College of Medicine1, Seoul, Korea Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute2, Seoul, Korea Seoul Municipal Boramae Hospital3, Seoul, Korea
Correspondence:  Eui Seok Han, M.D.
Abstract
PURPOSE
To evaluate the clinical characteristics and treatment result of Coats' disease in children. METHODS: Data on demographics, clinical presentation, and ocular findings were analyzed for 67 eyes of 67 patients with Coats' disease by retrospective chart review. Among these, treatment results were analyzed from 56 eyes which had received local treatment or subretinal fluid drainage (SRFD). Treatment was considered successful when telangiectatic vessels or exudates had regressed after local treatment or when pupillary block glaucoma was treated or prevented after SRFD. RESULTS: Mean age at diagnosis was 5.0 years (5 months-15 years) and 90% were males. 67% of retinal telangiectasias were located in the temporal. There were exudative retinal detachments in 46 (69%) eyes. Among them, SRFD was performed in 19 (28%) to treat or prevent pupillary block glaucoma. The mean age at diagnosis of patients that underwent treatment was 5.1 years. In 37 of 56 patients, 95% of retinal telangiectasias were regressed after primary local treatment, and 21 eyes (31%) underwent SRFD. Management of glaucoma was achieved after SRFD in 16 patients, and one more SRFD was needed after primary SRFD in 5 patients. CONCLUSIONS: In Coats' disease, it is necessary to eradicate retinal telangiectasia with local treatment and to follow up carefully for secondary glaucoma, which can be treated with SRFD in cases of severe exudative retinal detachment.
Key Words: Coats' disease;Cryotherapy;Laser photocoagulation;Pupillary block angle-closure glaucoma;Subretinal fluid drainage


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