| Clinical Aspects and Treatment Outcomes of Moraxella keratitis. |
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Yong Yeon Song, Sora Bang, Tae Eun Lee, Wan Seok Kang, In Cheon You |
1Department of Ophthalmology, Chonbuk National University Medical School, Jeonju, Korea. you2ic@daum.net
2Research Institute of Clinical Medicine, Chonbuk National University, Jeonju, Korea.
3Biomedical Research Institute, Chonbuk National University Hospital, Jeonju, Korea.
4Pureun Eye Center, Jeonju, Korea. |
| 모락셀라 각막염의 임상양상과 치료 결과 |
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송용연1⋅방소라1⋅이태은1,2,3⋅강완석4⋅유인천1,2,3 |
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전북대학교 의과대학 안과학교실1, 전북대학교 임상의학연구소2, 전북대학교병원 의생명연구원3, 전주푸른안과4 |
Correspondence:
In Cheon You,
Email: you2ic@daum.net
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Received: 21 September 2017 • Revised: 12 November 2017 • Accepted: 19 February 2018 |
| Abstract |
PURPOSE
To analyze the clinical presentation, predisposing risk factors, and evaluate the treatment outcomes of Moraxella keratitis. METHODS: A retrospective analysis was conducted of 12 culture positive cases of Moraxella keratitis from hospital records between March 2001 and November 2015 at a tertiary hospital to identify and analyze its risk factors, causative microbial organisms, clinical features, and therapeutic outcomes. RESULTS: The mean patient age was 68 years (range, 46–86). The most common cause of keratitis was trauma (six eyes, 50.0%), and half of these patients had diabetes mellitus (three patients, 25.0%). Two patients (16.6%) were previously treated with penetrating keratoplasty. The locations of keratitis involved the central (50.0%) and paracentral (50.0%) regions. Round-shaped corneal infiltration was found in seven eyes (58.3%), and irregular-shaped infiltration was found in five eyes (41.7%). Hypopyon was observed in five eyes (41.7%). All Moraxella isolates were susceptible to aminoglycosides and fluoroquinolones. The isolates from three patients were resistant to trimethoprim/sulfamethoxazole. The mean complete epithelial healing time was 32.4 days. The final visual acuity was 20/1,000 or less in seven eyes (58.3%). Three eyes developed corneal perforations and eventually underwent evisceration. CONCLUSIONS: In the Republic of Korea, Moraxella keratitis frequently occurs in eyes with trauma. The treatment response is very slow and has a poor visual outcome; thus, a long period of antibiotic therapy is necessary. |
| Key Words:
Moraxella keratitis;Predisposing factor;Trauma;Treatment outcome |
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