| Clinical Features and Surgical Treatment Outcomes of Conjunctival Squamous Papilloma. |
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Chan Joo Ahn, Nam Ju Kim, Ho Kyung Choung, Joon Young Hyon, Sang In Khwarg |
1Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea. khwarg@snu.ac.kr
2Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
3Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea.
4Department of Ophthalmology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.
5Seoul Artificial Eye Center, Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea. |
| 결막 편평상피유두종의 임상양상과 수술적 치료의 결과 |
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안찬주1⋅김남주2,3⋅정호경2,4⋅현준영2,3⋅곽상인1,2,5 |
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서울대학교병원 안과1, 서울대학교 의과대학 안과학교실2, 분당서울대학교병원 안과3, 서울대학교병원운영 서울특별시보라매병원 안과4, 서울대학교병원 임상의학연구소 서울인공안구센터5 |
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| Abstract |
PURPOSE
To investigate the clinical features, surgical treatments, and their outcomes in conjunctival squamous papilloma. METHODS: A retrospective chart review was conducted on 31 patients with 32 eyes that were treated for conjunctival papilloma from October 2000 to February 2015 in Seoul National University Hospital and Seoul National University Bundang Hospital. RESULTS: Among the 31 patients, 9 patients had papilloma which recurred after previous surgical excision at another hospital. Twenty-five eyes had one papilloma lesion, 2 eyes had 2 lesions, and 5 eyes had more than 3 lesions. The most affected location of papilloma was the tarsal conjunctiva. The recurrent group displayed a tendency to have multiple lesions. Surgical excision without any adjuvant therapy was performed in 13 eyes; surgical excision and cryotherapy in 15 eyes; surgical excision, cryotherapy, and topical interferon alfa-2b in 3 eyes; and surgical excision and amniotic membrane transplantation in 1 eye. The mean postoperative follow up period was 11.1 months. There were 5 cases of recurrence and the mean time of recurrence after surgical excision was 4.22 months (range, 3 days to 9 months). Among 5 cases of recurrence, 3 cases were after surgical excision only, 1 case was after surgical excision and cryotherapy, and 1 case was after surgical excision, cryotherapy, and topical interferon alfa-2b. These 5 recurred cases were retreated with surgical excision and cryotherapy, surgical excision and topical interferon alfa-2b, or surgical excision, cryotherapy, and topical interferon alfa-2b. CONCLUSIONS: Conjunctival squamous papilloma is likely to recur even though the tumor is completely removed. Therefore, long-term postoperative follow up may be necessary for recurrence. |
| Key Words:
Conjunctival papilloma;Conjunctival squamous papilloma;Cryotherapy;Interferon alfa-2b;Surgical excision |
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