Antibiotic Susceptibilities of Ocular Isolates from Patients with Bacterial Ke ratitis: A Multi-center Study.

Hahn, Young Ho; Lee, Sang Joon; Hahn, Tae Won; Tchah, Hungwon; Kim, Jae Chan

Original Article

Journal of the Korean Ophthalmological Society 1999;40(9):2401-2410.
Published online September 1, 1999.

Antibiotic Susceptibilities of Ocular Isolates from Patients with Bacterial Ke ratitis: A Multi-center Study.

Young Ho Hahn, Sang Joon Lee, Tae Won Hahn, Hungwon Tchah, Jae Chan Kim

Department of Ophthalmology, Gospel Hospital, The Kosin University, Pusan, Korea.

세균각막염에서 원인균주에 대한 항생제감수성검사 :다병원연구

한영호(Young Ho Hahn),이상준(Sang Joon Lee),한태원(Tae Won Hahn),차흥원(Hung Won Tchah),김재찬(Jae Chan Kim)

Abstract

This multi-center study was performed prospectively to evaluate the causative organisms and antibiotic sensitivity of isolates in bacterial keratitis from April 1995 to December 1998. Total number of infectious keratitis was 1002 cases. Among them,279 cases were confirmed with bacterial keratitis and 314 strains were identified. Major causative organisms of bacterial keratitis were Pseudomonas aeruginosa 121 strains (38.54%), coagulase negative staphylococcus (CNS) 34 strains (10.83%), Streptococcus pneumoniae 19 strains (6.81%), Staphylococcus aureus 18 strains (5.73%), and Serratia marscence 16 strains (5.10%). P.aeruginosa was highly sensitive to ciprofloxacin, ceftazidime, piperacillin, cefoperazone, imipenem,tobramicin,and gentamycin. Coagulase negative streptococcus showed high sensitivity to vancomycin, teicoplanin, clindamycin, and ciplofloxacin, but low sensitivity to penicillin and gentamycin. In conclusion, the choice of the effective antibiotics in the treatment of bacterial keratitis were essential to decrease resistant bacterial strains.

Key Words: Antibiotics;Bacterial keratitis;Sensitivity test