Journal of the Korean Ophthalmological Society 2000;41(7):1499-1508.
Published online July 1, 2000.
Epidemiology of Fungal Keratitis in Korea: A Multi-center Study.
Young Ho Hahn, Dong Jun Lee, Man Soo Kim, Si Hwan Choi, Jae Duck Kim
1Department of Ophthalmology, Gospel Hospital, The Kosin University.
2Department of Ophthalmology, Kangnam St.Mary's Hospital, Catholic University Medical College, Seoul, Korea.
3Department of Ophthalmology, College of Medicine, Chungnam National University, Daejeon, Korea.
4Department of Ophthalmology, College of Medicine, Wonkwang University, Iksan, Korea.
한국인에서 진균각막염의 역학조사 : 다병원연구
한영호(Young Ho Hahn),이동준(Dong Jun Lee),김만수(Man Soo Kim),김재덕(Jae Duck Kim),최시환(Si Hwan Choi)
Abstract
Fungal keratitis, one of devastating microbial keratitis, is difficult to diagnose and treat successfully. The authors performed prospectively an epidemiological study in Korea to identify the risk factors and to evaluate clinical manifestations, methods and results of treatment in fungal keratitis under the identical protocol from April 1995 to September 1999. Logistic regression analysis was used to evaluate possible risk factors. Sixty eight cases of fungal keratitis, which were identified by culture with corneal scraping or corneal biopsy and reported in 22 hospitals, were studied. The major causative organisms were Fusarium spp.(20 cases), Aspergillus spp.(17 cases), and Candida spp.(11 cases). The principal risk factors of fungal keratitis identified in this study were farmer, use of long-standing topical corticosteroids, and diabetes mellitus. Old age and corneal trauma with vegetable matters were the associated factors in fungal keratitis. Further evaluation of the risk factors and the establishment of the prevention in fungal keratitis are required.
Key Words: Epidemiology;Fungal keratits;Fusarium species;Risk factors


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