Primary Intraocular T-cell Lymphoma.

Shin, Yong Il; Kim, Ju Mi; Lee, Jong Joo; Kim, Jung Yeul; Kim, Jinman; Jo, Young Joon

doi:2019.60.6.594

J Korean Ophthalmol Soc > Volume 60(6); 2019 > Article

Case Report

Journal of the Korean Ophthalmological Society 2019;60(6):594-599.
DOI: https://doi.org/10.3341/jkos.2019.60.6.594 Published online June 15, 2019.

Primary Intraocular T-cell Lymphoma.

Yong Il Shin, Ju Mi Kim, Jong Joo Lee, Jung Yeul Kim, Jinman Kim, Young Joon Jo

¹Department of Ophthalmology, Chungnam National University College of Medicine, Daejeon, Korea. youngjoonjo@gmail.com
²Department of Pathology, Chungnam National University College of Medicine, Daejeon, Korea.

원발 안구 내 T세포 림프종

신용일¹·김주미¹·이종주¹·김정열¹·김진만²·조영준¹

충남대학교 의과대학 안과학교실¹, 충남대학교 의과대학 병리학교실²

Correspondence: Young-Joon Jo, MD, PhD
Email: youngjoonjo@gmail.com

Received: 20 September 2018 • Revised: 6 November 2018 • Accepted: 16 May 2019

Abstract

PURPOSE
Intraocular lymphoma can be divided into primary and secondary usually involving B-cell lymphoma. Intraocular T-cell lymphoma is mostly secondary lymphoma while primary intraocular T-cell lymphoma is extremely rare. We report a case of primary T-cell lymphoma. CASE SUMMARY: A 62-year-old male without any systemic disease presented with a floater in the right eye. A fundus examination showed multiple whitish retinal infiltrations in the right eye. Intraocular lymphoma was suspected, and systemic examination was performed, but all results were normal. During steroid treatment, previous lesions were enlarged, new lesions developed, and a diagnosis of primary T-cell lymphoma was made by diagnostic vitrectomy. Consecutive intravitreal injections of methotrexate were performed. After eight injections, the vitreous and retinal lesions improved but we decided to terminate the injections due to corneal epitheliopathy. The corneal epitheliopathy was recovered and the patient is currently undergoing periodic follow-ups without progression of the lesion. CONCLUSIONS: Although intraocular T-cell lymphoma is a rare condition, this primary T-cell type should be considered when an intraocular lymphoma lesion is suspected.

Key Words: Corneal epitheliopathy;Methotrexate;Primary intraocular T-cell lymphoma