A Case of Inferior Rectus Muscle Enlargement after Taking Sildenafil Citrate.

Jung, Youn Hea; Lee, Na Young; Yim, Hye Bin

doi:2013.54.2.382

J Korean Ophthalmol Soc > Volume 54(2); 2013 > Article

Case Report

Journal of the Korean Ophthalmological Society 2013;54(2):382-386.
DOI: https://doi.org/10.3341/jkos.2013.54.2.382 Published online February 28, 2013.

A Case of Inferior Rectus Muscle Enlargement after Taking Sildenafil Citrate.

Youn Hea Jung, Na Young Lee, Hye Bin Yim

Department of Ophthalmology, The Catholic University of Korea Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Incheon, Korea. yimhb@catholic.ac.kr

Sildenafil Citrate 복용 후 발생한 하직근 비대 1예

정윤혜⋅이나영⋅임혜빈

Department of Ophthalmology, The Catholic University of Korea Incheon St. Mary’s Hospital,
The Catholic University of Korea College of Medicine, Incheon, Korea

Abstract

PURPOSE
Sildenafil citrate was developed to treat angina, but was found to also inhibit PDE in the corpus callosum and is now widely used to treat impotence. We report a case of enlargement of the inferior rectus muscle after sildenafil citrate ingestion. CASE SUMMARY: A 58-year-old male presented with binocular diplopia which started 2 weeks prior. He had no underlying disease. The patient had taken sildenafil citrate on 3 different occasions 2 weeks prior, and 2 days after his first ingestion, his right conjunctiva was injected and binocular diplopia started. On the first visit, he showed 16 PD hypotropia of the right eye with limitation of motion at upgaze. The MRI scan showed enlargement and enhancement of the inferior rectus muscle, and 50 mg of prednisone was prescribed. The amount of hypotropia decreased to 8 PD 2 weeks later. CONCLUSIONS: Enlargement of extraocular muscle caused by sildenafil citrate ingestion has not been reported in Korea, and related mechanisms are yet to be researched. Additional case reports and research are necessary in the future.

Key Words: Myositis;Sildenafil citrate;Strabismus;Viagra