A Case of Bilateral Branch Retinal Vein Occlusion after Taking Tamoxifen.

Lee, Jeffrey; Yeom, Myeong In; Lee, Chang Kyu; Park, Jung Min

doi:2016.57.11.1806

J Korean Ophthalmol Soc > Volume 57(11); 2016 > Article

Case Report

Journal of the Korean Ophthalmological Society 2016;57(11):1806-1811.
DOI: https://doi.org/10.3341/jkos.2016.57.11.1806 Published online November 15, 2016.

A Case of Bilateral Branch Retinal Vein Occlusion after Taking Tamoxifen.

Jeffrey Lee, Myeong In Yeom, Chang Kyu Lee, Jung Min Park

¹Department of Ophthalmology, Maryknoll Medical Center, Busan, Korea. pjm1438@hanmail.net
²Department of Ophthalmology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.

타목시펜 복용 후 발생한 양안 망막분지정맥폐쇄 1예

이상곤¹⋅염명인¹⋅이창규²⋅박정민¹

메리놀병원 안과¹, 울산대학교 의과대학 울산대학교병원 안과학교실²

Abstract

PURPOSE
To report a case of bilateral branch retinal vein occlusion development after taking long-term tamoxifen adjuvant therapy. CASE SUMMARY: A 72-year-old female breast cancer patient with a 10-year history of tamoxifen intake presented with decreased visual acuity that began 5 years prior. The patient had no other past history. The best corrected visual acuity (BCVA) was 0.3 in the right eye and 0.04 in the left eye. There was no specific finding of anterior segment on slit lamp examination. On fundus examination, sheathed branch retinal veins were observed in the inferotemporal area of the right eye and superotemporal and inferotemporal areas of the left eye. Microangiopathies were observed around the occluded branch retinal veins in both eyes and macular edema was present in the left eye. Laser photocoagulation was performed at the non-perfusion area in both eyes and an intravitreal injection of bevacizumab and 3 intravitreal injections of triamcinolone were administered into the left eye. The BCVA did not change after 3 years and remained relatively stable. CONCLUSIONS: If a patient presents with decreased visual acuity after taking tamoxifen, fundus examination and fluorescein angiogram should be performed due to the possibility of branch retinal vein occlusion.

Key Words: Bilateral branch retinal vein occlusion;Breast cancer;Tamoxifen