A Case of Multiple Eyelid Trichilemmoma Associated with Cowden Syndrome.

Cho, Chan Ho; Son, Jun Hyuk

doi:2013.54.5.803

J Korean Ophthalmol Soc > Volume 54(5); 2013 > Article

Case Report

Journal of the Korean Ophthalmological Society 2013;54(5):803-807.
DOI: https://doi.org/10.3341/jkos.2013.54.5.803 Published online May 15, 2013.

A Case of Multiple Eyelid Trichilemmoma Associated with Cowden Syndrome.

Chan Ho Cho, Jun Hyuk Son

Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, Korea. sjh@med.yu.ac.kr

코우덴 증후군과 연관된 다발성 눈꺼풀 모종 1예

조찬호⋅손준혁

Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, Korea

Abstract

PURPOSE
To report a case of multiple eyelid trichilemmomas associated with Cowden syndrome. CASE SUMMARY: A 27-year-old woman presented with multiple upper and lower eyelid skin masses that developed over several years. The masses were as large as whitish millet, and were around the upper and lower eyelid margin and the face. The patient had previously undergone subtotal thyroidectomy for a thyroid mass and a mass excision for extremity hemangioma. Excisional biopsy was performed for the diagnosis, and trichilemmoma was diagnosed based on histopathologic examination. Consequently, multiple trichilemmoma associated with Cowden syndrome was diagnosed, and breast evaluations for existence of further masses were recommended. On breast examinations, intraductal papilloma and fibroadenoma were detected. CONCLUSIONS: The trichilemmoma was a hair-follicle benign tumor that also appeared on the skin around the eyelid. If multiple trichilemmoma is diagnosed, an association with Cowden syndrome should be considered as well as presence of masses in other organs.

Key Words: Cowden syndrome;Eyelid mass;Trichilemmoma