| Intravitreal Bevacizumab Injection in Adult Coats' Disease. |
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Young Sook Park, Jun Hong Sohn, Han Woong Lim, Byung Ro Lee |
1Department of Ophthalmology, HanGil Eye Hospital, Incheon, Korea.
2Department of Ophthalmology, College of Medicine, Hanyang University, Seoul, Korea. Brlee@hanyang.ac.kr |
| 성인 코우츠병에서 유리체강내 베바시주맙 주입술 2예 |
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박영숙1ㆍ손준홍1ㆍ임한웅2ㆍ이병로2 |
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Department of Ophthalmology, HanGil Eye Hospital1, Incheon, Korea Department of Ophthalmology, College of Medicine, Hanyang University2, Seoul, Korea |
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| Abstract |
PURPOSE
To report the efficacy of intravitreal bevacizumab injection in adult patients with Coats' disease. CASE SUMMARY: Vascular telangiectasia, microaneurysms, circinate hard exudates, and macular edema were shown in the macula of two patients. Vascular abnormality was limited to < or =6 clock hours in both cases. In case 1, the temporal retina demonstrates filigree-like vessels and capillary nonperfusion. In case 2, the nasal retina demonstrates aneurysmal dilatation and multiple microaneurysms. Intravitreal bevacizumab injection was administered in both cases. After 1 month, macular edema decreased. Laser photocoagulation was performed for vascular telangiectasia, microaneurysms, and capillary nonperfusion area. Then an additional decrease of macular edema was observed. Fluorescein leakage decreased, as well. After 1 month (case 1) and 2 months (case 2), macular edema increased. The second and third intravitreal reinjections were administered to each patient. Macular edema decreased. CONCLUSIONS: We report two rare cases of Coats' disease in adult patients. Intravitreal bevacizumab injection in patients with Coats' disease can result in a rapid decrease of macular edema, which will then lead to rapid visual recovery and an opportunity for effective laser photocoagulation. We recommend that intraviteal bevacizumab injection be used in combination with laser photocoagulation for the treatment of Coats' disease. |
| Key Words:
Coats' disease;Intravitreal bevacizumab injection;Laser photocoagulation |
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