Follow-Up Changes of Multifocal Electroretinogram in a Patient with Vogt-Koyanaki-Harada Syndrome.

Lim, Sang Hyun; Park, Su Eun; Park, Tae Kwann; Ohn, Young Hoon

Case Report

Journal of the Korean Ophthalmological Society 2006;47(3):494-499.
Published online March 31, 2006.

Follow-Up Changes of Multifocal Electroretinogram in a Patient with Vogt-Koyanaki-Harada Syndrome.

Sang Hyun Lim, Su Eun Park, Tae Kwann Park, Young Hoon Ohn

Department of Ophthalmology, Soonchunhyang University College of Medicine, Gyeonggi, Korea. eyedrlim@paran.com

보크트-고야나기-하라다 증후군 환자 1예에서 치유 경과에 따른 다국소망막전위도 변화

임상현,박수은,박태관,온영훈

Department of Ophthalmology, Soonchunhyang University College of Medicine, Gyeonggi, Korea

Correspondence: Sang Hyun Lim, M.D.

Abstract

PURPOSE
To assess the changes of retinal function together with recovery progress in a patient with Vogt-Koyanaki-Harada syndrome using a multifocal electroretinogram (mfERG). METHODS: The retinal changes of a 32-year-old woman diagnosed with Vogt-Koyanaki-Harada syndrome have been investigated and compared for different times such as before treatment and 3 and 6 months after treatment using a fluorescein angiogram, electroretinogram (ERG) and mfERG. RESULTS: As time passed, the patient's visual acuity was recovered, the serous retinal detachment in the posterior pole was restored, and the phenomenon of late subretinal leakage disappeared on fluorescein angiogram, while aggregation and atrophy of the retinal pigment epithelium were detected. The early-stage responses of the retina decreased on ERG; however, it has gradually recovered and was determined to be normal after 6 months. Responses measured on the mfERG have increased during the 6 months after surgery compared to the pre-treatment, but there was still a partial lack of response. CONCLUSIONS: In this case, the abnormal condition of retinal function existed continuously on the mfERG, even when the serous retinal detachment in the posterior pole was recovered. In this regard, a long-term systematic investigation and subsequent mfERG treatment have been thought to be necessary for patients with this disease.

Key Words: ERG;mfERG;Retinal pigment epithelium;Vogt-Koyanagi-Harada syndrome