| Needle Revision with and without Mitomycin C for the Teatment of Failed Filtering Blebs after Trabeculectomy. |
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In Ho Roh, Sung Min Hyung |
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Department of Ophthalmology, School of Medicine, Chungbuk National University, Chungbuk, Korea. smh@chungbuk.ac.kr |
| 섬유주절제술 후 여과포형성에 실패한 환자에서 마이토마이신씨를 이용한 주사침복원술의 효과 |
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노인호,형성민 |
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Department of Ophthalmology, School of Medicine, Chungbuk National University, Chungbuk, Korea |
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Correspondence:
In Ho Roh, M.D. |
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| Abstract |
PURPOSE
To evaluate the effects of needle revision (NR) with and without mitomycin C (MMC) for failed filtering blebs after trabeculectomy, and to identify risk factors for failure. METHODS: Thirty-one eyes whose intraocular pressure (IOP) did not decrease after cutting of scleral flap sutures were recruited. NR was performed with a 26-gauge needle under a slit-lamp. Immediately following NR, 15 eyes received subconjunctival injection of 0.002 mg (0.02 mg/ml) MMC at the adjacent conjunctiva. RESULTS: First NR was done at 1.3+/-1.2 months (range, 0.2~6.5 months) after trabeculectomy, and a mean of 1.6+/-1.6 NRs per patient were done. The follow-up period was 24.4+/-20.4 months (range, 6.0~87.4 months) after the last NR. Pre-NR mean IOP was 27.9+/-11.6 mm Hg and post-NR final IOP was 18.8+/-13.0 mm Hg (p=0.005). The success rate, defined as IOP < or =18 mm Hg with or without medication, was 80.3% (25 eyes of 31 eyes). The success rate was higher in the group receiving NR with adjunctive MMC (100%) than in the group receiving NR without MMC (62.5%) (p=0.018). Patients who underwent trabeculectomy without adjunctive MMC and those who had pre-NR IOP >25 mm Hg showed a higher failure rate, though with no statistical significance (p=0.141 and p=0.173, respectively). CONCLUSIONS: NR followed by subconjunctival injection of MMC is an effective and safe method for the treatment of the failed filtering blebs after trabeculectomy. Trabeculectomy without adjunctive MMC and pre-NR IOP higher than 25 mmHg were risk factors for failure of NR. |
| Key Words:
Filtering bleb;Mitomycin C;Needle revision |
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