Chronic Granulomatous Inflammation of the Eye lids.

Son, Moo Gon; Kim, Yoon Duck

Original Article

Journal of the Korean Ophthalmological Society 2000;41(6):1279-1285.
Published online June 1, 2000.

Chronic Granulomatous Inflammation of the Eye lids.

¹Department of Ophthalmology, Asan Medical Center, Ulsan University College of Medicine, Korea.
²Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

안검에 발생한 만성육아종성 염증

손무곤(Moo Gon Son),김윤덕(Yoon Duck Kim)

Abstract

Granulomatous inflammation is characterized by granuloma formation with a cellular infiltrate of epithelioid cells, giant cells, and chronic inflam-matory cells.It could be diagnosed as a subtype of inflammatory pseudotumor when such identifiable causes of granulomatous inflammation have been ruled out. We performed excisional biopsy on 3 patients who complained of upper eyelid mass.The levator muscle was mainly affected in two patients and the lacrimal gland in one patient. Microscopic examination of the mass demonstrated chronic granulomatous inflammation including non-caseating necrosis, diffuse chronic inflammatory cell infiltrates, and granuloma com-posed of histiocytes, multinucleated giant cells, lymphocytes, and epithelioid cells in all 3 patients.There was no evidence of foreign material and infec-tion with tuberculosis, mycosis, and parasites.The diagnosis of sarcoidosis, connective tissue disease, and Wegener's granulomatosis could be ruled out through the basic hematological test, chest radiograph, and blood tests such as angiotensin converting enzyme, lysozyme, antinuclear antigen, and anti-neutrophil cytoplasmic antibody. We experienced 3 cases of chronic granulomatous inflammation of the eyelids without identifiable causes which responds to excision and postoperative steroid therapy without recurrences.

Key Words: Granulomatous;Lid;Pseudotumor