Epidemiology of infectious Keratitis[I] A Multi-center Study.

Hahn, Young Hoo; Hahn, Tae Won; Choi, Si Hwan; Choi, Kee yong; Wee, Won Ryang; Kim, Ki San; Kim, Hyo Myung; Tchah, Hung Won; Chung, Jang Hyun; Lee, Ha Bum; Kim, Jae Duck; Kim, Jae Chan; Jin, Kyung Hyun; Yun, Young Su; Myong, Yoon Won; Chung, Wung Kun; Joo, Choun Ki; Kim, Man Soo; Ko, Myung Kyoo; Kim, Eung Kweon; Lee, Jong Hyuck; Kim, Hyung Jun; Lee, Jin Hak

Original Article

Journal of the Korean Ophthalmological Society 1998;39(8):1633-1651.
Published online August 1, 1998.

Epidemiology of infectious Keratitis[I] A Multi-center Study.

Young Hoo Hahn, Tae Won Hahn, Si Hwan Choi, Kee yong Choi, Won Ryang Wee, Ki San Kim, Hyo Myung Kim, Hung Won Tchah, Jang Hyun Chung, Ha Bum Lee, Jae Duck Kim, Jae Chan Kim, Kyung Hyun Jin, Young Su Yun, Yoon Won Myong, Wung Kun Chung, Choun Ki Joo, Man Soo Kim, Myung Kyoo Ko, Eung Kweon Kim, Jong Hyuck Lee, Hyung Jun Kim, Jin Hak Lee

Department of Ophthalmology, Kangnam St. Mary`s Hospital, Catholic University Medical College.

감염성 각막염의 역학조사[I] : 다병원연구

한영호(Young Ho Hahn),한태원(Tae Won Hahn),최시환(Si Hwan Choi),최기용(Kee yong Choi),위원량(Won Ryang Wee),김기산(Ki San Kim)

Abstract

Infectious keratitis is the most common serious ocular infection, and may be caused by various bacteria, fungi, viruses and parasites. The authors performed prospectively an epidemiological study to identify risk factors and causative organisms, and to evaluate clinical manifestations, methods and results of treatment in infectious keratitis under the identical protocol from April 1995 to September 1997. Logistic regression analysis [univariate analysis and multivariate analysis] was used to evaluate possible risk factors. Six hundred sixty cases of infectious keratitis reported from 19 hospitals were studied. Two hundred eighty-three organisms[247 bacteria, 32 fungi, 4 acanthamoeba] were detected in 626 eyes with infectious keratitis excluding 34 pherpetic keratitis. The Pseudomonas aeruginosa, coagulase negative staphylococcus, Staphylococcus aureus and Serratia marcescens were the major orgnisms in bacterial keratitis. Aspergillus, Fusarium and Candida were the major isolates in fungal keratitis. Contact lens wear was a risk factor for bacterial keratitis. Female, age[less than 40 years] and occupation[student, house-wife, office worker, servise] were associated with bacterial keratitis. Risk factors in herpetic keratitis were age[between 40 and 59 years] and ocular adnexal diseases. Male was associated factor with herpetic keratitis.

Key Words: Epidemiology;infectious keratits;Logistic regression analysis;Risk factors