Journal of the Korean Ophthalmological Society 1993;34(3):225-229.
Published online March 1, 1993.
Needling with 5-Fluorouracil for the Treatment of Non-Functioning Functioning Filtering Blebs.
Joon Sang Kim, Jong In Chung, Young Jae Hong
Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
기능이 없는 누공수술 여과포에 대한 5-FU 주사를 병용한 Needling 처치
홍영재(Young Jae Hong),정종인(Jong In Chung),김준상(Joon Sang Kim)
Abstract
The functional loss of bleb due to fibrosis after trabeculeetomy is not rare in glaucoma patients but it is possible the restore to function of bleb with simple treatment. The authors reviewed 15 eyes of 14 patients at least 6 months follow up after the needling and 5-FU injection for the non-functioning bleb after trabeculectomy, in terms of intraocular pressure control and complication. After needling of the non-functioning bleb, 5-FU was used 2mg dosage at one time and average total dosage of 12mg, subconjunctivally. The intraocular pressure was controlled under 21mmHg in 12 of 15 eyes (80%) after this procedure with or without medication. The complication observed is a corneal epithelial defect in 3 of 15 eyes (20%). Therefore, the needling and 5-FU injection for non-functioning bleb after trabeculectomy is recommended before reoperation because it is simple and safe method.
Key Words: 5-FU;Needling;Non-functioning bleb;Trabeculectomy


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