A Case of Carcinoma Ex Pleomorphic Adenoma at 1st Operation.

Jeon, Soo Ji; Kim, Su Ah; Paik, Ji Sun; Yang, Suk Woo

doi:2015.56.4.598

J Korean Ophthalmol Soc > Volume 56(4); 2015 > Article

Case Report

Journal of the Korean Ophthalmological Society 2015;56(4):598-601.
DOI: https://doi.org/10.3341/jkos.2015.56.4.598 Published online April 15, 2015.

A Case of Carcinoma Ex Pleomorphic Adenoma at 1st Operation.

Soo Ji Jeon, Su Ah Kim, Ji Sun Paik, Suk Woo Yang

Department of Ophthalmology and Visual Science, The Catholic University of Korea College of Medicine, Seoul, Korea. yswoph@hanmail.net

일차 수술에서 발견된 다형성 샘암종 1예

전수지⋅김수아⋅백지선⋅양석우

가톨릭대학교 의과대학 안과 및 시과학교실

Abstract

PURPOSE
To report a case of carcinoma ex pleomorphic adenoma observed during the patient's first operation. CASE SUMMARY: A 63-year-old female presented with proptosis and ptosis that was aggravated 1 year prior. On preoperative CT image, a 32 x 20 x 21 mm-sized well demarcated mass (suspected as pleomorphic adenoma) was observed and was removed entirely by anterolateral orbitotomy. The excised mass surface was uneven but the capsule appeared intact on gross examination. Hard, yellow-colored and soft, dark-colored materials were found concurrently on cross section. The histological examination showed malignant cells as part of the soft material and was diagnosed as carcinoma ex pleomorphic adenoma. CONCLUSIONS: We report a case of carcinoma ex pleomorphic adenoma of the lacrimal gland that presented with malignant change during the patient's first operation. Supposedly, during the process of mass growth, minimal rupture occurred causing malignant transformation. Clinically, although a mass is believed benign based on imaging, the possibility of malignant transformation of a tumor increasing rapidly or enlargement causing development of rapid proptosis should be considered.

Key Words: Carcinoma ex pleomorphic adenoma;Lacrimal gland tumor;Malignant mixed tumor;Pleomorphic adenoma