Primary Orbital MALT Lymphoma Associated with Localized Amyloidosis.

Lyu, In Jeong; Woo, Kyung In; Kim, Yoon Duck

doi:2013.54.7.1109

J Korean Ophthalmol Soc > Volume 54(7); 2013 > Article

Case Report

Journal of the Korean Ophthalmological Society 2013;54(7):1109-1113.
DOI: https://doi.org/10.3341/jkos.2013.54.7.1109 Published online July 15, 2013.

Primary Orbital MALT Lymphoma Associated with Localized Amyloidosis.

In Jeong Lyu, Kyung In Woo, Yoon Duck Kim

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. ydkimoph@skku.edu

국소 아밀로이드증(Amyloidosis)이 동반된 안와 점막연관 림프조직형 림프종(MALT lymphoma) 1예

유인정⋅우경인⋅김윤덕

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Abstract

PURPOSE
To report a case of primary orbital MALT lymphoma with localized amyloidosis. CASE SUMMARY: A 61-year-old male visited our clinic with diplopia, which had developed approximately 5 months earlier. Magnetic resonance imaging of the orbit showed an ill-defined well-enhanced mass in the left inferior orbit. Incisional biopsy of the orbital mass was performed. Histopathological examination revealed diffuse deposits of an amorphous, eosinophilic substance in the extracellular matrix and vessels with lymphocytes infiltration. Lymphocytes were positive for the immunohistochemical stain against the CD20 and kappa-light chain antigens. The amorphous material stained positive for kappa-light chain antigen, and Congo red staining showed birefringence. CONCLUSIONS: We report a rare case of primary orbital MALT lymphoma associated with localized amyloidosis.

Key Words: Amyloidosis;MALT lymphoma