J Korean Ophthalmol Soc > Volume 55(2); 2014 > Article
Journal of the Korean Ophthalmological Society 2014;55(2):252-260.
DOI: https://doi.org/10.3341/jkos.2014.55.2.252    Published online February 15, 2014.
Long-Term Outcomes of Trabeculectomy in Korean Patients with Juvenile Open-Angle Glaucoma.
Eun Kyu Oh, Eun Ji Lee, Jin Wook Jeoung, Seok Hwan Kim, Tae Woo Kim, Ki Ho Park, Dong Myoung Kim
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. opticdisc@gmail.com
2Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
3Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul National University College of Medicine, Seoul, Korea.
한국인 연소성개방각녹내장 환자에서 섬유주절제술의 장기 성적
오은규1⋅이은지1,2⋅정진욱1⋅김석환1,3⋅김태우1,2⋅박기호1⋅김동명1
Department of Ophthalmology, Seoul National University College of Medicine1, Seoul, Korea
Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine2, Seongnam, Korea
Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul National University College of Medicine3, Seoul, Korea
Abstract
PURPOSE
To evaluate the outcomes and prognostic factors of trabeculectomy with mitomycin C in Korean patients with juvenile open-angle glaucoma (JOAG). METHODS: A retrospective review was performed on 29 eyes with JOAG who had undergone trabeculectomy between January 2004 and January 2013. Intraocular pressure (IOP) and postoperative complications were monitored at 1 day preoperatively, at 1 day, 1 week, 1 month, 3 months, 6 months, and 12 months postoperatively, and at final follow-up after postoperative 18 months. Surgical success was defined as a final IOP of <21 mm Hg or <80% of preoperative IOP, regardless of the use of anti-glaucoma medication. Prognostic factors for surgical success or failure were analyzed by the Cox proportional hazards model. RESULTS: Mean (+/- standard deviation) age at trabeculectomy was 24.6 (+/- 8.9) years, and mean follow-up period was 24.3 (+/- 20.8) months. The overall success rate was 82.8% at final follow-up. The Kaplan-Meier cumulative probabilities of surgical success were 100% at 1 year, 87.4% at 2 years, and 78.7% at 3 years postoperatively. The Cox proportional hazards model failed to determine any significant factors that were associated with surgical failure. The three most frequent postoperative complications were immediately postoperative hypotony (n = 19, 65.5%), hypotony maculopathy (n = 8, 27.6%), and encapsulated bleb (n = 8, 27.6%), most of which were resolved after a minor procedure or observation. Two of 8 eyes with encapsulated bleb required a second surgery. There were no vision-threatening severe complications. CONCLUSIONS: Trabeculectomy with MMC may be an effective treatment in Korean JOAG patients.
Key Words: Juvenile open-angle glaucoma;Prognostic factor;Surgical outcomes;Trabeculectomy


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