J Korean Ophthalmol Soc > Volume 52(8); 2011 > Article
Journal of the Korean Ophthalmological Society 2011;52(8):984-989.
DOI: https://doi.org/10.3341/jkos.2011.52.8.984    Published online August 15, 2011.
Combined Mitomycin-C Assisted Photorefractive Keratectomy in the Treatment of Epithelial Ingrowth after LASIK.
Hye Young Shin, Kyong Jin Cho, Man Soo Kim
Department of Ophthalmology and Visual Science, The Catholic University College of Medicine, Seoul, Korea. mskim@catholic.ac.kr
마이토마이신을 병용한 치료적 레이저각막절제술을 이용한 라식 후 발생한 상피내생의 치료
신혜영⋅조경진⋅김만수
Department of Ophthalmology and Visual Science, The Catholic University College of Medicine, Seoul, Korea
Abstract
PURPOSE
To report 2 cases of thick, late-onset and long-standing epithelial ingrowth after laser-assisted in situ keratomilusis (LASIK) using mitomycin C-assisted photorefractive keratectomy and flap suturing. CASE SUMMARY: The first case involved a 29-year-old woman who had LASIK in both eyes in 2002. She was diagnosed with epithelial ingrowth OD after blunt ocular trauma in 2007. The second case involved a 30-year-old man who had LASIK in both eyes in 1999 followed by enhancements in 2004. Slit lamp examination showed dense epithelial ingrowth OS in a geographic pattern. Two eyes of the 2 patients with epithelial ingrowth had flap lifting followed by debridement of interface epithelial cells, photorefractive keratectomy, interface application of mitomycin C, and the placement of interrupted 10-0 nylon sutures. Two eyes regained better uncorrected visual acuity and showed reduced corneal astigmatism postoperatively. There was no evidence of residual or recurrent ingrowth throughout the follow-up period (case 1: 11 months, case 2: 1 month). CONCLUSIONS: Combined mitomycin C-assisted photorefractive keratectomy and flap suturing can be an effective and safe method for treating and preventing the recurrence of thick, late-onset and long-standing epithelial ingrowth involving the visual axis.
Key Words: Epithelial ingrowth;LASIK complication;Mitomycin C;Phototherapeutic keratectomy


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