J Korean Ophthalmol Soc > Volume 51(1); 2010 > Article
Journal of the Korean Ophthalmological Society 2010;51(1):29-34.
DOI: https://doi.org/10.3341/jkos.2010.51.1.29    Published online January 15, 2010.
Correlation Between Multifocal Electroretinography and Visual Acuity After Resolution of Diabetic Macular Edema.
Kwan Hoon Lee, Moo Hwan Chang, Jung Hyun Ahn
Department of Ophthalmology, Dankook University College of Medicine, Cheonan, Korea. changmh@dankook.ac.kr
당뇨황반부종에서 다국소 망막전위도검사와 치료 후 시력과의 상관관계
이관훈ㆍ장무환ㆍ안정현
Department of Ophthalmology, Dankook University College of Medicine, Cheonan, Korea
Abstract
PURPOSE
To evaluate the prognostic value of multifocal electroretinography (mfERG) after a decrease of retinal thickness in eyes with diabetic macular edema (DME). METHODS: Sixty patients (60 eyes) underwent intravitreal injection of triamcinolone acetonide or bevacizumab for diabetic macular edema. Eyes were divided into three groups, according to foveal thickness : Group A (<500 micrometer, n=20 eyes), Group B (500 micrometer <== <800 micrometer, n=20 eyes), and Group C (>==800 micrometer, n=20 eyes). Best-corrected visual acuity (BCVA) and mfERG responses from the most central seven hexagons were analyzed both before and after treatment. RESULTS: The pre-injection P1 amplitudes of mfERG correlated significantly with end-point BCVA in Groups A and B (p<0.05), but did not correlate with end-point BCVA (p>0.05) in Group C. CONCLUSIONS: The level of P1 amplitudes of mfERG may be a useful tool to predict visual outcomes after a decrease of retinal thickness in patients with diabetic macular edema.
Key Words: Diabetic macular edema;Multifocal electroretinography;Visual acuity


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