A Case of Primary Cuteaneous CD30-Positive Lymphoproliferative Disorder of the Eyelid.

Lee, Sang Hun; Lew, Helen; Shim, Jeong Yun

Case Report

Journal of the Korean Ophthalmological Society 2005;46(7):1222-1227.
Published online July 31, 2005.

A Case of Primary Cuteaneous CD30-Positive Lymphoproliferative Disorder of the Eyelid.

¹Department of Ophthalmology, Pochun CHA University College of Medicine, Pundang CHA Hospital, Sungnam, Korea. eye@cha.ac.kr
²Department of Pathology, Pochun CHA University College of Medicine, Pundang CHA Hospital, Sungnam, Korea.

안검에 발생한 원발성 피부 세포표면항원무리 30 양성 림프구증식 질환1예

이상흔¹,유혜린¹,심정연²

Department of Ophthalmology¹ and Pathology², Pochun CHA University College of Medicine, Pundang CHA Hospital, Sungnam, Korea

Correspondence: Sang-Hun Lee, M.D.¹

Abstract

PURPOSE
To report one case of lymphoproliferative disorder on the upper eyelid. METHODS: Primary CD30+ lymphoproliferative disorder on the skin is very rare. A 31-year-old female patient visited our clinic complaining of red, erosive papules on the right upper eyelid and on the left flank for two weeks. A 2.0 cm erythematous papule showed central ulceration. A 1.5 cm lymph node enlargement was palpated on the left groin. There was no abnormal finding on the slit-lamp test. Computed tomography showed a subcutaneous nodule on the anterolateral aspect of the flank and a lymph node enlargement on the left inguinal area. There was no evidence of other visceral involvement. Histopathologic finding showed diffuse infiltration of atypical cells with lobated nuclei showing multifocal positivity to CD30; a finding consistent with primary cutaneous CD30+ T-cell lymphoproliferative disorder and borderline lesion. RESULTS: This case seems to be a borderline case between CD30+ T-cell large cell lymphoma and lymphoid papulodesis. We are conducting conservative care and observing the progress on the skin lesion for further evaluation.

Key Words: Borderline case;CD30;Large cell lymphoma;Lymphoid papulodesis