Journal of the Korean Ophthalmological Society 2006;47(11):1865-1870.
Published online November 30, 2006.
Infectious Endophthalmitis After Intravitreal Injection of Triamcinolone Acetonide.
Hee Jin Sohn, Dong Heun Nam
Department of Ophthalmology, Gachon University of Medicine and Science, Gil Medical Center, Incheon, Korea. eyedawns@gilhospital.com
유리체강내 트리암시놀론 주사 후 발생한 감염성 안내염 2예
손희진,남동흔
Department of Ophthalmology, Gachon University of Medicine and Science, Gil Medical Center, Incheon, Korea
Correspondence:  Hee Jin Sohn, M.D.
Abstract
PURPOSE
We report 2 cases of infectious endophthalmitis after intravireal triamcinolone acetonide injection which was successfully treated with early vitrectomy. METHODS: A 56 year old male patient with chronic cystoid macular edema of right eye and an 84 year old female patient with diabetic macular edema of right eye (pseudophakic) eye were treated with intravireal triamcinolone acetonide injection. Four days after the injection, both the patients complained of decreased visual acuity that had been developed 1 and 2 days prior respectively. Visual acuity was hand motion, inflammatory cells, flare, fibrins and hypopyon were found in the anterior chamber. Fundus was not visible due to vitreous opacity. RESULTS: The two patients were presumed to have infectious endophthalmitis. Anterior chamber irrigation, vitrectomy, intravitreal antibiotics injection, and vitreous culture were performed. Coagulase negative staphylococcus was detected from vitreous culture, Within 1 week of the follow-up procedures, the anterior chamber and vitreous inflammation were improved and visual acuity recovered to the level attained before intravireal triamcinolone acetonide injection. CONCLUSIONS: If after intravireal triamcinolone acetonide injection, there is severely decreased visual acuity, inflammation of the anterior chamber and vitreous, flare and fibrin are detected, infectious endophthalmitis must be suspected. If diagnosed early and treated with vitrectomy, a favorable visual prognosis is expected.
Key Words: Infectious endophthalmitis;Iintravireal injection;Triamcinolone acetonide


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