Journal of the Korean Ophthalmological Society 2005;46(2):306-315.
Published online February 28, 2005.
Glaucoma Discrimination by Combined Use of Frequency Doubling Technology and Heidelberg Retina Tomography II.
Ho Ra, Chan Kee Park
Department of Ophthalmology, Kangnam St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. ckpark@catholic.ac.kr
주파수 배가 시야검사계와 하이델베르그 시신경 유두 분석기 II의 복합분석을 이용한 녹내장 판별
나호,박찬기
Department of Ophthalmology, Kangnam St. Mary`s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
Correspondence:  Ho Ra, M.D.
Abstract
PURPOSE
This study investigated whether the combined use of Frequency Doubling Technology and Heidelberg Retina Tomography II increases the usefulness of glaucoma detection. METHODS: The study subjects were, 59 patients with POAG and 34 normal persons were selected. The authors defined a total of six discriminative criteria: F1, in which the conventional analysis of FDT was used; F2, in which the FDT scoring system was used; F3, in which the Moorfield classification of HRT was used; F4, in which the new HRT discrimination function `Z' was used; F5, in which F1 and F3 were combined, and F6, in which F2 and F4 were combined; The usefulness of each criterion was investigated. RESULTS: The sensitivity, specificity, and area under the ROC curve of the six discriminative criteria were: 86.4%, 58.8%, and 0.740 in F1, 4.5%, 80.0% (cutoff: 12.50), and 0.882 in F2, 79.7%, 61.8%, and 0.679 in F3, 77.6%, 74.3% (cutoff: 0), and 0.857 in F4, 77.6%, 71.4% (cutoff: 1.0805), and 0.767 in F5, and 86.2%, 91.4% (cutoff: 0.495) and 0.931 in F6. CONCLUSIONS: Combined use of functional (FDT) and morphological (HRT) aspects, which are early parameters of glaucoma damage, gave more useful results than a single analysis of each. Thererfore, the combined use will help the early detection of glaucoma.
Key Words: Frequency doubling technology;Heidelberg retina tomography


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