Bacteriologic Study on Normal Conjunctival Flora and Change of Antibiotic Susceptability.

Park, Hyung Jun; Yi, Ga Young; Moon, Nam Ju

Original Article

Journal of the Korean Ophthalmological Society 2001;42(6):817-824.
Published online June 1, 2001.

Bacteriologic Study on Normal Conjunctival Flora and Change of Antibiotic Susceptability.

Hyung Jun Park, Ga Young Yi, Nam Ju Moon

National Medical Center, Department of Ophthalmology.

결막낭 내의 세균균총 및 항생제에 대한 감수성 변화

이가영(Ga Young Yi),문남주(Nam Ju Moon),박형준(Hyung Jun Park)

Abstract

We evaluated the distribution of normal conjuctival flora and the change of antibiotic sensitivity of cultured bacteria. Specimens were obtained from inferior conjunctiva cul de sac with sterile cotton-tipped applicator from healthy 216 human beings. Antibiotic sensitivity test was done by disk diffusion method. The results indicated that overall positive culture rate was 47.7% and major organisms were Coagulase-negative Staphylococcus(55.7%), Staphylococcus aureus(16%), Gram negative bacteria(7.5%), Streptococcus(4.7%). Antibiotic sensitivity test of cultured Gram positive bacteria demonstrated less than 60% rate of susceptability in gentamicin, tetracyclin, erythromycin and 80.5% rate of susceptability in ciprofloxacin. Gram negative bacteria demonstrated less than 60% rate of susceptability in cephalothin, ampicillin. From the above results, we concluded that antibiotic resistance of normal conjunctival flora was increased from the past and the principle of antiviotic eye drop use should be emphasized.

Key Words: Antibiotic sensitivity;Normal conjunctival flora;Resistance of antibiotics