Histological Progress Observation of Conjunctival MALToma.

Byon, Doseok; Moon, Yoensung; Kim, Jongseon; Kwak, Hyukjin

Original Article

Journal of the Korean Ophthalmological Society 2002;43(3):443-448.
Published online March 1, 2002.

Histological Progress Observation of Conjunctival MALToma.

Doseok Byon, Yoensung Moon, Jongseon Kim, Hyukjin Kwak

Department of Ophthalmology, Medical College, Inha University, Korea. byoneye@medigate.net

결막의 점막 연관 림프종의 조직학적 경과 관찰

변도석 ( Do Seok Byon ) , 문연성 ( Yoen Sung Moon ) , 김종선 ( Jong Seon Kim ) , 곽혁진 ( Hyuk Jin Kwak )

Abstract

PURPOSE
We report six cases of histologically diagnosed conjunctival MALT (mucosa-associated lymphoid tissue)oma. Presenting symptoms were eyelid swelling, foreign body sensation, lid mass, injection and itching sensation. PATIENTS AND METHODS: Six patients with conjunctival MALToma were followed. Clinical progress and biopsy result were reviewed periodically. RESULTS: The conjunctival MALToma seemed to be localized and slowly progressive. Although the conjunctival MALToma is known to be well responsive to radiotherapy, two of three patients who received radiotherapy revealed to have remnant lymphoma cells histologically in conjunctival biopsy. In addition, chemotherapy did not have curative effect in any of the patients. CONCLUSIONS: Therefore, we are doubtful for the necessity of active treatment in MALTomas of the conjunctiva.

Key Words: Chronic conjunctivitis;Conjunctival MALToma;Low grade malignant lymphoma