Journal of the Korean Ophthalmological Society 1998;39(12):3053-3062.
Published online December 1, 1998.
Tracing Study on Neuroaxis of Medial Rectus Muscle in the Brain Stem of the White Rat.
Hong Bum Lee, Sung Wook Suh, Ji Myong Yoo
Department of Ophthalmology, College of Medicine, Gyeongsang National University.
흰쥐 뇌줄기에서 내직근 지배신경로의 추적 연구
이홍범(Hong Bum Lee),서성욱(Seong Wook Sch),유지명(Ji Myung Yoo)
Abstract
To clarify neuronal connection of the medial rectus muscle at brain stem, Bartha strain of the psecudorabies virus(PRV-Ba) and cholera toxin-horeserdish peroxidase(CT-HRP) was injected into medial rectus muscle of the rat. About 84 hours after PRV or CT-HRP injection, the brain was removed and processed immunohistochemical stain for PRV-Ba and neurohistochemical stain for CT-HRP using tetramethyl benzidine. The CT-HRP positive reaction was only present in ipsilateral oculomotor nucleus, contralateral abducence nucleus and bilaterally in rostral interstitial nucleus of medial longitudinal fasciculus, olivary pretectal nucleus, medial and superior vestibular nucleus, nucleus prepositus hypoglossi, prerubral field, nucleus Darkschewitsch, lateral substantia nigra, terminal nucleus of accessory nucleus, dorsal raphenucleus, locus ceruleus and pontime reticular formation. This study confirmed that both oculomotor nucleus and abducence nucleus were connected with each other through the medial longitudinal fasciculus, and neuronal connection of the medial rectus muscle in the rat brain stem.
Key Words: CT-HRP;Medial rectus muscle;Neuronal connection;PRV-Ba
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