The Combined Effect of Physical Barriers and 5-Fluorouracil on Delayed Adjustable Strabismus Surgery.

Hwang, Jeong Min; Chang, bong Leen

Original Article

Journal of the Korean Ophthalmological Society 1999;40(1):211-218.
Published online January 1, 1999.

The Combined Effect of Physical Barriers and 5-Fluorouracil on Delayed Adjustable Strabismus Surgery.

Jeong Min Hwang, bong Leen Chang

Department of Ophthalmology, seoul Municipal Boramae Hospital.

물리적 장벽과 5-Fluorouracil의 병용요법의 지연 조정효과

황정민(Jeong Min Hwang),장봉린(Boong Leen Chang)

Abstract

In order to prevent the formation of postoperative adhesions and delay the time of adjustment, the authors tried 5-fluorouracil and physical barriers of polytetrafluoroethylene, Interceed, Viscoat in rabbits. Fluorouracil delayed the adjustment for up to one week after surgery in three out of four eyes. Combined use of Interceed and 5-fluorouracil of addition of Viscoat could delay the adjustment for up to two weeks after surgery I one out of four eyes. Combined use of pophtetrafluoroethylene and 5-fluorouracil of addition of Viscoat could delay the adjustment for up to four weeks after surgery in four out of five eyes. In conclusion, combined use of polytetrafluoroethylene, 5-fluorouracil and Viscoat could be more helpful for delayine adjustment in rabbits.

Key Words: Adjustment;5-fluorouracil;Interceed;Polytetrafluoroethylene;Viscoat