Expression of Strabismus in Monozygotic Twins.

Lee, Chang Hun; Kim, Myung Mi

Original Article

Journal of the Korean Ophthalmological Society 1999;40(3):824-828.
Published online March 1, 1999.

Expression of Strabismus in Monozygotic Twins.

Chang Hun Lee, Myung Mi Kim

Department of Ophthalmology, Yeungnam University College of Medicine.

일란성 쌍둥이에서 사시의 발현

이창훈(Chang Hun Lee),김명미(Myung Mi Kim)

Abstract

We have studied the concordance of strabismus in monozygotic twins to determine the influence of genetic inheritance in expression of strabismus. We examined 21 pairs of monozygotic twins(32 strabismic patients of 42). The average age was 5.5 years(2 months-23 years) at their first visit. Out of 21 pairs of monozygotic twins, 11 pairs were concordant(52%) in type of strbismus: 6 pairs in intermittent exotropia, 2 pairs in infantile estropia, and 3 pairs in partially accommodative esotropia. Not a single pair of twins were concordant in accommodative esotropia, dissociated vertical deviation, or superior oblique palsy. This study suggests that expression of strabismus in monozygotic twins may be discordant and that it is not determined merely by genetic inheritance, but also by various other factors. And those conceordant pairs in type results, and recurrence.

Key Words: Monozygotic twins;Strabismus