Amiodarone Induced Keratopathy. |
Jun Ho Heo, Ji Young Kim, Chul Ho Kim |
Department of Ophthalmology, Seoul Municipal Boramae Hospital. |
Amiodarone 각막병증 |
허준호(Jun Ho Heo),김지영(Ji Young Kim),김철호(Chul Ho Kim) |
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Abstract |
Amidarone hydrochloride, benzofuran derivatives, particularly effective for the treatment of arrythmias by prolong the duration of the action potential in all cardiac-conducting tissues. We studied the 25 patients with typical amiodarone keratopathy, retrospectively. In 25 patients, ten patients developed grade 1, eleven patients developed grade 2, and four patients developed grade 3 keratopathy. They complained of decreased best corrected visual acuity(1 patient), halos(1 patient), hypothyroidism(3 patients), pulmonary toxicity(2 patients), thpatic dysfunction(5 patients) and sleep dusturbance(3 patients). Therefore ophthalmologists should be alert for the complications of amiodarone and regular careful slit-lamp examination will be helpful in minimizing amidarone toxicity. |
Key Words:
Amiodarone;Amiodarone keratopathy;Amiodarone toxicity |
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