A Case of Stevens-Johnson Syndrome after Acetazolamide Use.

Lee, Jong Hyuck; Lee, Seok Joon; Kim, Yoon Heui

Case Report

Journal of the Korean Ophthalmological Society 1998;39(1):216-220.
Published online January 1, 1998.

A Case of Stevens-Johnson Syndrome after Acetazolamide Use.

Jong Hyuck Lee, Seok Joon Lee, Yoon Heui Kim

Department of Ophthalmology, Yonsei University Wonju College of Medicine.

Acetazolamide 로 유발된 Stevens - Johnson 증후군 1예

이종혁(Jong Hyuck Lee),이석준(Seok Joon Lee),김윤희(Yoon Heui Kim)

Abstract

Erythema multiforme is an episodic, self-limited, mucocutaneous, inflammatory disorder and the disease manifests as severe form is called Stevens-Johnson syndrome. It is most commonly precipitated by herpes simplex infection or drugs and the pathogenesis of the mucocutaneous lesion is thought to be related to immune complexes, cell-mediated immunity, or both. We experienced a case of Stevens-Johnson syndrome in 23-year-old female who had systemic bullous kin lesion and diffue mucopurulent conjunctivitis after use of oral acetazolamide for control of steroid-induced increased intraocular pressure after excimer laser photorefractive keratectomy, which has not been reported in Korea. So, we report this case with a review of the literature.

Key Words: Acetazolamide;Excimer laser photorefractive keratectomy;Stevens-Johnson syndrome