Trabeculectomy with Mitomycin C in Congenital Glaucoma.

Lee, In Sik; Chung, Hak Sung; Hong, Young Jae

Original Article

Journal of the Korean Ophthalmological Society 1997;38(3):417-423.
Published online March 1, 1997.

Trabeculectomy with Mitomycin C in Congenital Glaucoma.

In Sik Lee, Hak Sung Chung, Young Jae Hong

Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.

선천녹내장에서 Mitomycin C를 병용한 섬유주절제술

이인식(In Sik Lee),정학성(Hak Sung Chung),홍영재(Young Jae Hong)

Abstract

We assessed the efficacy of trabeculectomy with mitomycin C in the management of congenital glaucoma of which prognosis is known to be poor. Twelve consecutive eyes of 7 primary congenital glaucoma patients who underwent trabeculectomy with mitomycin C were retrospectively reviewed. The mean age was 3.2 years(ranging from 1 to 10 years) and the mean follow-up period was 31.6 months (ranging from 15 to 42 months). The mean postoperatie intraocular pressure (IOP) at the end of follow-up period was 11.0 +/-3.0mmHg, significantly lower than the mean preoperative IOP which was 25.4 +/-6.3mmHg (P<0.01). The overall success rate was 50% after a single procedure. All the 6 failed eyes underwent the same operation again and the overall success rate was 83%. The complications included hypotony in 4 eyes (33.3%) and shallow anterior chamber in 2 eyes (16.6%), and they were all resolved spontaneously. There was no evidence of hypotonic maculopathy and endophthalmitis. Trabeculectomy with mitomycin C successfully lowered the IOP in congenital glaucoma patients without serious complication and further investigation will be required to determine ling-term effects in terms of successful filtration and possible late complications.

Key Words: Congenital glaucoma;Mitomycin-C;Trabeculectomy