The Effect of Absorbable Cellulose(Interceed, TC7) in Prevention of Adhesion in Strabismus Surgery in Rabbits.

Jung, Sang Yeop; Min, Byung Moo

Original Article

Journal of the Korean Ophthalmological Society 1997;38(5):849-855.
Published online May 1, 1997.

The Effect of Absorbable Cellulose(Interceed, TC7) in Prevention of Adhesion in Strabismus Surgery in Rabbits.

Sang Yeop Jung, Byung Moo Min

Department of Ophthalmology, College of Medicine, Chungnam National University, Taejon, Korea.

가토의 외안근 수술부위에서 흡수성 셀룰로스(Interceed, TC7)의 유착방지 효과

정상엽(Sang Yeop Jung),민병무(Byung Moo Min)

Abstract

The formation of adhesion following strabismus surgery may result in restrictive ocular motility dysfunction. We performed conventional recessions of both inferior and superior rectus muscle in right eyes of 11 white rabbits as control group and a sheet of 2 x 2 mm absorbable cellulose(Interceed, TC7) was inserted between rectus muscle and conjunctiva in left eyes of 11 rabbits as interceed group in the hope of preventing postoperative adhesion. We examined conjunctival injection, corneal abrasion, scleral necrosis and discharge at 1st, 2nd day, 1st, 2nd, 4th, 6th week following surgery and examined muscle adhesion powers by spring gauge and degrees of adhesion by blunt disection and histopathologic examination with light microscope at 6th week. The postoperative corneal and conjunctival findings and muscle adhesion powers were similar but degrees of adhesion at both blunt dissection and histopathologic examination revealed statistically significant reduction of adhesion in absorbable cellulose group than control group. From these findings, it would appear that the use of absorbable cellulose is effective in preventing postoperative adhesion following strabismus surgery .

Key Words: Absorbable cellulose;Adhesion;Strabismus surgery