Protease Activities in Various Kinds of Enzymatic Cleaneers for Contact Lenses.

Kim, Jae Ho; Tanouchi, Hiroshi

Original Article

Journal of the Korean Ophthalmological Society 1987;28(6):1183-1189.
Published online June 1, 1987.

Protease Activities in Various Kinds of Enzymatic Cleaneers for Contact Lenses.

¹Department of Ophthalmology, Kangnam St. Mary's Hospital, Catholic University Medical College, Seoul, Korea.
²Ophtecs Corp., Tokyo 103, Japan.

콘택트렌즈의 여러가지 효소세정제에 대한 단백해능의 비교

김재호(Jae Ho Kim),전내박(Hiroshi Tanouchi)

Abstract

UV-absorption method was able to determine protease activities in various kinds of enzymatic cleaners. Bioclen G and O2 had high protease activeities at room temperature and were effective for artificial protein deposits; Bioclen G is safe for the eyes because enzyme was inactivated at 70 degrees C. Both products were better enzymatic cleaners for both hard and soft contact lenses. Hydrocare-F was effective for removing artificial protein deposits. For the sake of safety against the eyes, there was a problem in that this product had too high protease activity at 90 degrees C. Protease activities were generally lower or showed great variations at 10~30 degrees C for other products. These had lower cleaning effect for artificial protein deposits on rigid gas permeable contact lenses.