A Case of Bilateral Conjunctival Amyloidosis Treated with Mass Excision and Cryotherapy.

Kim, Boyun; Song, Ji Hye; Yang, Suk Woo; Kim, Man Soo

doi:2011.52.5.628

J Korean Ophthalmol Soc > Volume 52(5); 2011 > Article

Case Report

Journal of the Korean Ophthalmological Society 2011;52(5):628-632.
DOI: https://doi.org/10.3341/jkos.2011.52.5.628 Published online May 15, 2011.

A Case of Bilateral Conjunctival Amyloidosis Treated with Mass Excision and Cryotherapy.

Boyun Kim, Ji Hye Song, Suk Woo Yang, Man Soo Kim

Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, The Catholic University of Korea School of Medicine, Seoul, Korea. mskim@catholic.ac.kr

양안 결막 아밀로이드증 진단과 결막종괴절제 및 냉동치료술 1예

김보윤⋅송지혜⋅양석우⋅김만수

Department of Ophthalmology and Visual Science, Seoul St. Mary’s Hospital, The Catholic University of Korea School of Medicine, Seoul, Korea

Abstract

PURPOSE
To report the treatment results of mass excision and cryotherapy in a case of bilateral conjunctival amyloidosis. CASE SUMMARY: A 72-year-old man with conjunctival mass and foreign body sensations in both eyes visited our clinic. He was previously diagnosed with conjunctival lymphoma after conjunctival biopsy at another hospital. A yellow-pink colored mass was observed in the bulbar conjunctiva. A repeated conjunctival biopsy revealed the mass to be amyloid, consistent with the cervical lymph node biopsy results, and the diagnosis was changed to primary systemic amyloidosis. The patient was treated with melphalan and prednisolone; however, the ocular pain, symblepharon, and conjunctival mass progressed. A 360 degree conjunctivoperiotomy, mass excision, and repeated cryotherapy were performed in the more severely affected left eye. The patient was followed for one year, and there were no complications or progression of the conjunctival lesion. CONCLUSIONS: Conjunctival amyloidosis requires local pathologic confirmation as well as a systemic work-up. If surgical removal is necessary despite systemic treatment, mass excision and cryotherapy may be effective.

Key Words: Congo-red;Conjunctival amyloidosis;Cryotherapy