Tractional Retinal Detachment After Intravitreal Bevacizumab (Avastin(R)) Injection in Proliferative Diabetic Retinopathy. |
Hyun Jai Song, Hee Jin Sohn, Dae Yeong Lee, Dong Heun Nam |
Department of Ophthalmology, Gachon University Gil Hospital, Incheon, Korea. eyedawns@gilhospital.com |
증식당뇨망막병증 환자에서 유리체내 베바시주맙 주입술 후 발생한 견인망막박리 |
송현재ㆍ손희진ㆍ이대영ㆍ남동흔 |
Department of Ophthalmology, Gachon University Gil Hospital, Incheon, Korea |
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Abstract |
PURPOSE To report two cases of tractional retinal detachment after intravitreal bevacizumab injection. CASE SUMMARY: (Case 1) A 48-year-old female with insulin-dependent diabetes mellitus and a high HbA1c level came to our clinic for fundus evaluation. The best corrected visual acuity (BCVA) was 1.0 in the right eye and funduscopic examination of the right eye revealed proliferative diabetic retinopathy with preretinal hemorrhage and a mild fibrovascular proliferative membrane around the optic disc. Intravitreal bevacizumab injection (1.25 mg) was performed before starting panretinal photocoagulation (PRP) to prevent macular edema after PRP. Three days after the injection, visual acuity decreased to 0.3 and funduscopic findings showed tractional retinal detachment. Vitrectomy was performed and visual acuity recovered to 1.0 four months after operation. CONCLUSIONS: Intravitreal bevacizumab injection may cause tractional retinal detachment in poorly controlled insulin-dependent diabetes mellitus patients with fibrovascular proliferative membranes. |
Key Words:
Bevacizumab;Proliferative diabetic retinopathy;Tractional retinal detachment |