| The Anticollagenase Effect of Serum in Alkali-burned Cornea in Rabbit. |
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Dong Hwan Park, Byung Joo Yoon |
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Department of Ophthalmology, National Medical Center, Seoul, Korea. |
| 가토에서 각막의 알칼리 화상에 대한 자가혈청 내의 anticollagenase 의 치료 효과 |
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박동환(Dong Hwan Park),윤병주(Byung Joo Yoon) |
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| Abstract |
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The possible role of collagenase in the development of corneal ulcers has been intensively studied and collagenase inhibitors have been successfully used to control some corneal ulcers. They are cysteine, EDTA, proteoglycan, serum, and medroxyprogesteron, However, most of them are limited in clinical use because of their toxicity and instability except serum, which is not toxic to the host. We carried out an experiment with serum upon alkali-burned rabbit cornea. Serum has potent anticollagenase effect, and prevents corneal ulceration. |
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