A Case of Choroidal Metastasis from Renal Cell Carcinoma.

Park, Saemi; Choi, Sang Yul; Choi, Kyung Seek

doi:2012.53.6.880

J Korean Ophthalmol Soc > Volume 53(6); 2012 > Article

Case Report

Journal of the Korean Ophthalmological Society 2012;53(6):880-885.
DOI: https://doi.org/10.3341/jkos.2012.53.6.880 Published online June 15, 2012.

A Case of Choroidal Metastasis from Renal Cell Carcinoma.

Saemi Park, Sang Yul Choi, Kyung Seek Choi

¹Department of Ophthalmology, Soonchunhyang University College of Medicine, Seoul, Korea. ckseek@schmc.ac.kr
²Department of Ophthalmology, Korea Cancer Center Hospital, Seoul, Korea.

신세포암의 맥락막 전이 1예

박새미¹⋅최상열²⋅최경식¹

Department of Ophthalmology, Soonchunhyang University College of Medicine¹, Seoul, Korea
Department of Ophthalmology, Korea Cancer Center Hospital², Seoul, Korea

Abstract

PURPOSE
To report a rare case of choroidal metastasis from renal cell carcinoma. CASE SUMMARY: A 61-year-old man visited our clinic with the chief complaint of decreased vision in the right eye. Three years earlier, he underwent right nephrectomy due to renal cell carcinoma. Best corrected visual acuity was 0.2 in the right eye and 1.0 in the left eye. Fundoscopic examination of the right eye revealed a yellowish, dome-shaped elevated choroidal mass with serous retinal detachment, measuring 5.0 x 4.0 disc diameter and located lateral to the macular area. Systemic evaluations showed multiple lung and brain metastases. A diagnosis of choroidal metastasis from renal cell carcinoma was made for the right eye, and the patient received local treatments with oral sorafenib therapy, composed of subtenon triamcinolone injection and intravitreal ranibizumab injection. Tumor progression continued, and visual acuity declined to hand motion. Enucleation was recommended, but the patient refused and is on a regular follow-up after transpupillary thermotherapy. CONCLUSIONS: Ocular manifestation may be the initial presenting sign of a recurrent tumor, and an extensive systemic evaluation for metastatic malignancy should be performed. The present example showed a rare case of choroidal metastasis from renal cell carcinoma.

Key Words: Choroidal metastasis;Renal cell carcinoma