| Incidence and Characteristics of Acute Endophthalmitis Associated With Intravitreal Injection. |
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Hyun Jin Kim, Dong Won Lee, Hyo Jung Kang, Young Ju Lew, Moon Jeong Choi, Jung Il Han, Su Jin You, Sung Won Cho, Tae Gon Lee, Jae Heung Lee |
1Department of Ophthalmology, School of Medicine, Ewha Woman's University, Seoul, Korea.
2Myung Gok Eye Research Institute, Kim's Eye Hospital, Konyang University, Seoul, Korea. mediceye@kimeye.com
3Department of Ophthalmology, Konyang University College of Medicine, Seoul, Korea. |
| 유리체강내 주입술 후 급성 안내염의 발생 빈도와 임상 양상 |
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김현진1ㆍ이동원2ㆍ강효정3ㆍ유영주2ㆍ최문정2ㆍ한정일2ㆍ유수진2ㆍ조성원2ㆍ이태곤3ㆍ이재흥2 |
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Department of Ophthalmology, School of Medicine, Ewha Woman’s University1, Seoul, Korea / Myung Gok Eye Research Institute, Kim’s Eye Hospital, Konyang University2, Seoul, Korea / Department of Ophthalmology, Konyang University College of Medicine3, Seoul, Korea |
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| Abstract |
PURPOSE
To evaluate the incidence, causative organism, clinical features, and visual outcomes of acute endophthalmitis following intravitreal injection. METHODS: For all intravitreal triamcinolone acetonide, bevacizumab, and lucentis injections performed in our outpatient clinic between January 2006 and June 2008, the number of injections, indications, type of administered drugs, and method of injection were investigated. The medical records of the patients with acute endoththalmitis were reviewed retrospectively. RESULTS: The total number of intravitreal injections was 10,153. The incidence of acute endophthalmitis for all intravitreal injections was 0.020% (2/10,153) with 0.030% (1/3,383) for the triamcinolone acetonide, 0.015% (1/6,552) for the bevacizumab, and 0.000% (0/218) for the ranibizumab drug injections. Streptococcus species were confirmed in the bacterial culture of two eyes with acute endotphthalmitis. After early vitrectomy and intravitreal antibiotics injection, one eye maintained vision but the other eye developed phthisis. CONCLUSIONS: Although the incidence of acute endophthalmitis following intravitreal injections performed in outpatient clinics is very low, due to the potentially fatal visual outcome after endophthalmitis, careful attention to aseptic injection technique is mandatory. |
| Key Words:
Anti-VEGF;Endophthalmitis |
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