A Case of Granulocytic Sarcoma Involving the Forniceal Conjunctiva.

Lee, Hyun Soo; Park, Joo Wan; Yang, Suk Woo

Case Report

Journal of the Korean Ophthalmological Society 2006;47(6):986-990.
Published online June 30, 2006.

A Case of Granulocytic Sarcoma Involving the Forniceal Conjunctiva.

Hyun Soo Lee, Joo Wan Park, Suk Woo Yang

Department of Ophthalmology, College of Medicine, The Catholic University of Korea, Seoul, Korea. parkjw@catholic.ac.kr

결막낭에 발생한 과립구육종 1예

이현수,박주완,양석우

Department of Ophthalmology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Correspondence: Hyun Soo Lee, M.D.

Abstract

PURPOSE
We report a case of the granulocytic sarcoma located at the conjunctival fornix in a 10-year-old girl with acute myeloid leukemia, who was in complete remission after bone marrow transplantation. METHODS: A 10-year-old girl had a 1-week history of firm, dark brown conjunctival mass at lower fornix and mild lid swelling of the right eye. Several months previously she had had some chalazions at lower lid and a history of acute myeloid leukemia that was currently in complete remission after bone marrow transplantation. Other ocular manifestations were not specific. Excision of the conjunctival mass and a biopsy for diagnostic and therapeutic purposes were performed. RESULTS: The 12 x 6 x 5 mm-sized mass was totally excised. The pathologic examination was consistent with granulocytic sarcoma. Three weeks after the biopsy, the patient had a relapse of acute myeloid leukemia. She died 2 months later while undergoing intensive therapy. CONCLUSIONS: This condition should be considered in the diagnosis of granulocytic sarcoma in patients with a history of acute myeloid leukemia.

Key Words: Acute myeloid leukemia;Chalazion;Conjunctival mass;Granulocytic sarcoma