J Korean Ophthalmol Soc > Volume 55(2); 2014 > Article
Journal of the Korean Ophthalmological Society 2014;55(2):317-323.
DOI: https://doi.org/10.3341/jkos.2014.55.2.317    Published online February 15, 2014.
A Case of Dengue Fever with Macular Involvement.
Kyung Hyun Jin, Ji Yeon Ahn, Joon Ki Min, Jae Ho Shin, Sang Woong Moon
1Department of Ophthalmology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea. ophmoon@dreamwiz.com
2Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.
황반부를 침범한 뎅기열 1예
진경현1⋅안지연2⋅민준기2⋅신재호1⋅문상웅1
Department of Ophthalmology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine1, Seoul, Korea
Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine2, Seoul, Korea
Abstract
PURPOSE
To report a case of Dengue fever with bilateral macular edema and retinitis. CASE SUMMARY: A 31-year-old female was referred to our clinic with blurred vision. The patient had visited Bali, Indonesia approximately 2 weeks prior. Dengue fever was diagnosed at the Division of Infectious Disease because the patient's serum dengue virus antibodies test was positive for dengue viral IgM antibodies. The patient's best corrected visual acuity was 0.4 in the right eye and 0.6 in the left eye. Slit lamp examination showed inflammatory cells in the vitreous but not in the anterior segment of both eyes. Fundus examination showed thickening of the retina in both eyes as well as a splinter retinal hemorrhage in left eye. Fluorescein angiography revealed hyperfluorescence of the venule in the perifoveal vascular network of the left macula, and indocyanine green angiography showed early diffuse hyperfluorescence in both eyes. Standard automated perimetry showed an overall reduction of the visual field and an increase in scotoma in both eyes. At 1 week after the initial visit, the macular edema had not improved and the patient's vision had deteriorated, especially in left eye. To improve the macular edema and ocular inflammation, a subtenon triamcinolone acetonide injection in the left eye was administered. At 5 weeks after treatment, corrected visual acuity improved to 1.0 in both eyes. Ocular findings, such as macular edema and intraretinal hemorrhage were resolved. The patient did not complain of any remaining discomfort. However, standard automated perimetry revealed that a pericentral scotoma was still present in left eye. CONCLUSIONS: In the present study, the authors report a case of bilateral macular edema and retinitis at the posterior pole after dengue infection. The patient demonstrated a relatively positive response to steroid therapy in the left eye and to conservative treatment in the right eye.
Key Words: Dengue fever;Macular edema;Retinitis


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