J Korean Ophthalmol Soc > Volume 54(5); 2013 > Article
Journal of the Korean Ophthalmological Society 2013;54(5):752-756.
DOI: https://doi.org/10.3341/jkos.2013.54.5.752    Published online May 15, 2013.
Changes in Intraocular Pressure and Choroidal Thickness after Hemodialysis in Chronic Renal Failure Patients.
Jun Woo Chun, Seung Woo Lee
Department of Ophthalmology, Dongguk University College of Medicine, Gyeongju, Korea. meinkamf@hanmir.com
만성신부전 환자에서 혈액투석 후의 안압 및 맥락막두께의 변화
전준우⋅이승우
Department of Ophthalmology, Dongguk University College of Medicine, Gyeongju, Korea
Purpose: To evaluate the change of choroidal thickness and intraocular pressure (IOP) as a result of hemodialysis
Abstract
PURPOSE
To evaluate the change of choroidal thickness and intraocular pressure (IOP) as a result of hemodialysis with chronic renal failure patients. In addition, the correlation between the change of choroidal thickness and IOP were evaluated. METHODS: A total of 48 eyes of 48 chronic renal failure patients undergoing hemodialysis were included in the present study. IOP, blood pressure (systolic and diastolic), serum osmolality, central corneal thickness (CCT), and choroidal thickness were measured before and after hemodialysis. Choroidal thickness was measured using spectral domain ocular coherence tomography (SD-OCT). RESULTS: After hemodialysis, IOP significantly decreased from 14.9 +/- 2.3 mm Hg to 14.3 +/- 2.1 mm Hg (p < 0.001) and choroidal thickness significantly decreased from 352.2 +/- 31.6 microm to 306.6 +/- 29.0 microm (p < 0.001). The other factors that significantly decreased after hemodialysis included serum osmolality (p < 0.001) and blood pressure (p < 0.001) except CCT (p = 0.285). There was a positive correlation between changes in IOP and choroidal thickness after hemodialysis (r = 0.319, p = 0.027). CONCLUSIONS: Decreased choroidal volume and thickness due to fluid loss may be involved in the mechanism of decreased IOP during hemodialysis.
Key Words: Choroidal thickness;Hemodialysis;Intraocular pressure;Spectral domain ocular coherence tomography


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