Clinical Consideration of Prednisolone Induced Cataract.

Kim, Kyu Seop; Joo, Choun Ki

Original Article

Journal of the Korean Ophthalmological Society 2004;45(5):732-735.
Published online May 1, 2004.

Clinical Consideration of Prednisolone Induced Cataract.

Kyu Seop Kim, Choun Ki Joo

Department of Ophthalmology, College of Medicine, The Catholic University of Korea, Seoul, Korea. ckjoo@catholic.ac.kr

프레드니솔론 복용 후 발생한 후낭하 백내장의 임상적 고찰

김규섭 ( Kim Gyu Seob ) , 주천기 ( Ju Cheon Gi )

Abstract

PURPOSE
The purpose of this paper was to examine the correlation between the development of posterior subcapsular cataract and the dosage and duration of systemic steroid therapy. METHODS: Twenty-two eyes which underwent cataract surgery at our ophthalmologic department were enrolled, along with 20 randomly selected eyes, which received prednisolone therapy at least for 1 year. We examined prednisolone dosage, duration and systemic disorders. We compare daily prednisolone dosage, and duration between the subcapsular opacity group and the non-subcapsular opacity group. SPSS, with 2 way- ANOVA system, was used for statistical analysis. RESULTS: The development of posterior subcapsular cataract was correlated with the daily prednisolone dosage, but not with the duration of prednisolone therapy (p<0.05). CONCLUSIONS: Careful attention to the daily steroid dosage is required to prevent posterior subcapsular cataract formation.

Key Words: Cataract;Prednisolone;Systemic steroid