Journal of the Korean Ophthalmological Society 2003;44(3):755-759.
Published online March 1, 2003.
Fungal Keratitis Caused by Chromomycetes.
Yun Sang Kim, Young Soo Song, Jae Chan Kim
Department of Ophthalmology, Chung-Ang University, College of Medicine, Seoul, Korea. jck50ey@kornet.net
Chromomycetes 에 의한 진균성 각막염
김윤상 ( Yun Sang Kim ) , 송영수 ( Young Soo Song ) , 김재찬 ( Jae Chan Kim )
Abstract
PURPOSE
Chromomycetes is a plant parasite and one of the pigmented filamentous fungi, which rarely causes human infection. The authors report the first case of fungal keratitis caused by chromomycetes in korea. METHODS: A 65-year-old woman developed pain, redness, and an yellowish-brown infiltrate in her right eye. She had a history of corneal scratch by a pumpkin stalk and transferred by a local clinic after management for about 1 months. The clinical features suggested fungal keratitis, and the patient was undertaken surgical debridement with amniotic membrane graft and treated with oral terbinafine with natamycin and amphotericin B eyedrops. Surgically taken biopsy specimen was cultured. Amniotic membrane was removed after 1 week. After slight improvement of symptom, necrotizing ulceration was enlarged in spite of continuous antifungal therapy. Lamellar keratoplasty with amniotic membrane graft was done with antifungal therapy. Systemic agent was changed to fluconazole. Clinical improvement was achieved after about 2 months. The fungus was identified as Fonsecaea pedrosoi. RESULTS: Fungal keratitis was successfully treated with antifungal medication combined with amniotic membrane graft. CONCLUSIONS: This is a rare case of infectious keratitis caused by chromomycetes. But its clinical course was severe, so exact culture and identification following aggressive surgical and medical treatment was needed.
Key Words: Chromoblastomycosis;Chromomycosis;Corneal ulcer;Fonsecaea Pedrosoi;Fungal Keratitis;Keratochromomycosis;Mycotic Keratitis


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