Exophthalmos in Acute Myelocytic Leukemia.

Kim, Hong Bok; Kim, Ho Won

Case Report

Journal of the Korean Ophthalmological Society 1976;17(4):501-505.
Published online April 1, 1976.

Exophthalmos in Acute Myelocytic Leukemia.

Hong Bok Kim, Ho Won Kim

Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.

급성골수성 백혈병에 병발한 안구돌출증

김홍복 , 김호원 ( Hong Bok Kim , Ho Won Kim )

Abstract

In leukemia, exophthalmos may be caused by retrobulbar hemorrhage or leukemic cell deposit in the orbital cavity. Exophthalmos lead by orbital infiltration occurs frequently in acute and chronic lymphocytic leukemia but only rarely in myelocytic leukemia. Two-third of patient with myelocytic leukemia present with fundus changes such as papilledema, tortuous retinal vein and retinal hemorrhages. A 13 year old Korean girl with exophthalmos (O.S.) was found to have acute myelocytic leukemia in 2 months after she begun to have unilateral proptosis. Her both fundi were normal. She was improved by administration of cytoxan and prednisolon, and left exophthalmos was recovered by irradiation of Co60 on the left orbit.