Scleritis in a Patient with Castleman Disease. |
Jae Jung Lee, In Ho Lee, Kang Yeun Park, Sung Who Park, Ji Eun Lee |
1Department of Ophthalmology, Pusan National University School of Medicine, Yangsan, Korea. jlee@pusan.ac.kr 2Medical Research Institute, Pusan National University Hospital, Busan, Korea. 3Department of Ophthalmology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea. |
캐슬만병과 동반된 공막염 1예 |
이재정1,2⋅이인호1,2⋅박강윤3⋅박성후1,2⋅이지은1,2 |
부산대학교 의과대학 안과학교실1, 부산대학교병원 의생명연구원2, 인제대학교 의과대학 해운대백병원 안과학교실3 |
Correspondence:
Ji Eun Lee, Email: jlee@pusan.ac.kr |
Received: 10 May 2018 • Revised: 30 May 2018 • Accepted: 31 July 2018 |
Abstract |
PURPOSE To report a case of multicentric Castleman disease that presented with scleritis. CASE SUMMARY: A 42-year-old male presented with decreased visual acuity in the left eye. Castleman disease had been diagnosed 21 months before and treated with systemic steroids and combined chemotherapy. Best-corrected visual acuity (BCVA) of the left eye was 0.02 and the intraocular pressure was 42 mmHg. Scleral edema and corneal edema were noted using a slit lamp examination. The anterior chamber cell was 2+ according to Standardization of Uveitis Nomenclature criteria. The fundus was invisible due to the anterior segment lesion. After one month, scleritis developed in the right eye and the patient complained of ocular pain. Topical steroids and non-steroidal anti-inflammatory drugs were prescribed. Due to recurrent scleritis and anterior uveitis, cataract extraction and laser iridectomy were performed on the left eye, and systemic steroids and the antimetabolite methotrexate were started. After 9 years of follow-up, all medications were stopped and there was no recurrence of inflammation, with a BCVA of 1.0 in both eyes. CONCLUSIONS: Treatment of a patient with scleritis accompanied with Castleman disease using systemic steroids and methotrexate resulted in a good prognosis. |
Key Words:
Castleman disease;Scleritis |
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