J Korean Ophthalmol Soc > Volume 59(12); 2018 > Article
Journal of the Korean Ophthalmological Society 2018;59(12):1103-1107.
DOI: https://doi.org/10.3341/jkos.2018.59.12.1103    Published online December 15, 2018.
Effect of Intense Regulated Pulse Light on Thickness of Tear Film Lipid Layer and Dry Eye Syndrome.
Tae Young Gil, Gi Hyun Bae, Joo Young Kwag, Joo Hyun, Jin Seok Choi, Kyu Hong Pak, Sung Kun Chung
1Department of Ophthalmology, SahmYook Medical Center, Seoul, Korea.
2Saevit Eye Hospital, Goyang, Korea. eyekun@gmail.com
조절펄스광선조사가 눈물막 지질층 두께 및 안구건조증에 미치는 효과
길태영1⋅배지현1⋅곽주영2⋅현 주2⋅최진석2⋅박규홍2⋅정성근2
삼육서울병원 안과1, 새빛안과병원2
Correspondence:  Sung Kun Chung,
Email: eyekun@gmail.com
Received: 26 July 2018   • Revised: 10 September 2018   • Accepted: 27 November 2018
To evaluate the clinical effect of intense regulated pulse light (IRPL) and changes in tear film thickness in dry eye patients. METHODS: A retrospective study was conducted on 25 patients with Meibomian gland dysfunction who had subjective dry eye discomfort and whose tear film break-up time (TBUT) was < 10 seconds. All patients were treated with IRPL three times on days 1, 15, and 45. TBUT, Schirmer 1 test results, cornea staining score with fluorescein, ocular surface disease index (OSDI), and lipid layer thickness were measured and compared before and after the procedure. RESULTS: TBUT was significantly increased from 3.7 ± 1.2 s to 4.4 ± 2.1 s after IRPL (p = 0.03). Schirmer 1 test and cornea staining scores changed significantly (p < 0.01 and p = 0.01, respectively). OSDI also showed a statistically significant improvement from 39.5 ± 17.5 points to 30.4 ± 18.7 points (p = 0.01). However, no significant difference in lipid layer thickness was observed (p = 0.49). CONCLUSIONS: IRPL is an effective treatment modality to improve TBUT, Schirmer 1 test scores, cornea staining scores, and subjective dry eye symptoms.
Key Words: Dry eye syndrome;Intense pulse light (IPL);Intense regulated pulse light (IRPL);Lipid layer thickness (LLT);Lipiview

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