J Korean Ophthalmol Soc > Volume 59(12); 2018 > Article
Journal of the Korean Ophthalmological Society 2018;59(12):1137-1141.
DOI: https://doi.org/10.3341/jkos.2018.59.12.1137    Published online December 15, 2018.
Intracameral Epinephrine Injection after Phacoemulsification on Pupil Dilation during Phacovitrectomy for Proliferative Diabetic Retinopathy.
Sangbum Kim, Jongyeop Park, Jaeryung Shin, Seungwoo Lee
1Department of Ophthalmology, Dongguk University College of Medicine, Gyeongju, Korea. jazzhanul@hanmail.net
2Goheung Health Center, Goheung, Korea.
3Dongguk University College of Medicine, Gyeongju, Korea.
유리체절제술과 수정체유화술 동시 수술 시 백내장수술 후 앞방내 에피네프린 주입과 동공 확대
동국대학교 의과대학 안과학교실1, 고흥군 보건소2, 동국대학교 의과대학3
Correspondence:  Seungwoo Lee,
Email: jazzhanul@hanmail.net
Received: 19 July 2018   • Revised: 11 September 2018   • Accepted: 23 November 2018
We explored the mydriatic effects of injected intracameral epinephrine after phacoemulsification (PE) combined with phacovitrectomy to treat proliferative diabetic retinopathy (PDR). METHODS: We enrolled 96 patients (96 eyes) who underwent phacovitrectomy to treat PDR; we used ImageJ software to measure pupil sizes and the ratios of pupil to cornea area (PCA) before and after PE and after pars plana vitrectomy (PPV). We compared pupil sizes between those who received intracameral epinephrine (0.001% w/v) after PE but before PPV (study group, 46 eyes) and patients not so treated (control group, 50 eyes). RESULTS: The PCA ratios of the study group were 0.52 ± 0.11 before PE, 0.43 ± 0.12 after PE, and 0.51 ± 0.11 after PPV, respectively. Changes in pupil size were significant (p < 0.001, p < 0.001 respectively). The PCA ratios of the control group were 0.52 ± 0.10 before PE, 0.39 ± 0.15 after PE, and 0.43 ± 0.15 after PPV, respectively. Changes in pupil size after PE were significant (p = 0.011) but the change after PPV was not (p = 0.056). CONCLUSIONS: Intracameral epinephrine given after PE but before PPV effectively dilates the pupils during phacovitrectomy to treat PDR.
Key Words: Diabetic retinopathy;Epinephrine;Phacoemulsification;Pupil;Vitrectomy

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