J Korean Ophthalmol Soc > Volume 60(1); 2019 > Article
Journal of the Korean Ophthalmological Society 2019;60(1):32-39.
DOI: https://doi.org/10.3341/jkos.2019.60.1.32    Published online January 15, 2019.
The Effect of Preoperative Homatropine for Intraoperative Floppy Iris Syndrome in Patients Taken Alpha Blockers.
Hyun Sik Moon, Jung Han Choi, Byung Yi Ko, Kyung Chul Yoon
1Department of Ophthalmology, Chonnam National University Medical School, Gwangju, Korea. kcyoon@jnu.ac.kr
2Department of Ophthalmology, Konyang University College of Medicine, Daejeon, Korea.
알파차단제를 복용하는 환자의 백내장수술 시 홍채이완증후군에 대한 호마트로핀 점안제의 효과
문현식1⋅최정한1⋅고병이2⋅윤경철1
전남대학교 의과대학 안과학교실1, 건양대학교 의과대학 안과학교실2
Correspondence:  Kyung-Chul Yoon
Email: kcyoon@jnu.ac.kr
Received: 28 June 2018   • Revised: 29 August 2018   • Accepted: 28 December 2018
Abstract
PURPOSE
To investigate the effects of homatropine eye drops before cataract surgery to prevent intraoperative floppy iris syndrome (IFIS) in patients treated with alpha blockers. METHODS: The medical records of 98 eyes from 68 patients taking alpha blockers who underwent cataract surgery were retrospectively reviewed and divided into three groups: patients with preoperative instillation of homatropine (group 1), patients with preoperative instillation of atropine (group 2), and patients without preoperative eye drops (group 3) for three days. Age, sex, underlying disease, type of alpha blocker, preoperative and postoperative pupil size, parameters of phacoemulsification, surgical complication, and the degree of IFIS of patients were measured to compare among the three groups. RESULTS: No significant differences were found in age and underlying diseases. Significant differences were found in the preoperative and postoperative pupil size, cumulative dissipated energy, and the incidence rate of iris prolapse through the incision sites among the three groups, but no significant difference was detected in other findings, or with regard to intraoperative or postoperative complications. In addition, the preoperative pupil size and preoperative instillation of 1% atropine were significant factors for decreasing the degree of IFIS. CONCLUSIONS: Preoperative instillation of homatropine as well as atropine before cataract surgery minimized the degree of IFIS in patients taking alpha blockers. In addition, the pupil size recovered more rapidly after surgery in the homatropine group than in the atropine group.
Key Words: Alpha blocker;Cataract;Homatropine;Intraoperative floppy iris syndrome


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